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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
22.42
Human Site:
S272
Identified Species:
44.85
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
S272
L
A
L
A
L
S
Q
S
E
A
E
E
K
E
R
Chimpanzee
Pan troglodytes
XP_511742
777
85768
E272
A
L
A
L
S
Q
S
E
A
E
E
K
E
R
L
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
S272
L
A
L
A
L
S
Q
S
E
A
E
E
K
E
R
Dog
Lupus familis
XP_540486
782
86005
E276
L
S
Q
S
E
A
E
E
K
E
R
M
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
S272
L
A
L
A
L
S
Q
S
E
A
E
E
K
E
R
Rat
Rattus norvegicus
Q9JJ50
776
86228
S272
L
A
L
A
L
S
Q
S
E
A
E
E
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
S272
L
A
I
A
L
S
Q
S
E
A
E
E
K
E
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
L270
K
E
E
E
E
L
Q
L
A
L
A
L
S
Q
S
Honey Bee
Apis mellifera
XP_393989
830
92147
S271
L
A
I
A
L
S
Q
S
E
A
E
H
Q
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
D269
L
A
M
A
L
S
L
D
E
A
E
N
K
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
D174
P
A
D
W
I
D
S
D
A
C
M
I
C
S
K
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
D269
P
R
D
A
R
V
D
D
S
F
D
E
D
L
K
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
6.6
73.3
N.A.
60
P-Site Similarity:
100
20
100
60
N.A.
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
13.3
93.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
9
67
0
9
0
0
25
59
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
0
0
17
0
0
9
9
25
0
0
9
0
9
0
0
% D
% Glu:
0
9
9
9
17
0
9
17
59
17
67
50
9
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
0
17
0
9
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
9
0
0
9
50
0
34
% K
% Leu:
67
9
34
9
59
9
9
9
0
9
0
9
0
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
59
0
0
0
0
0
9
17
0
% Q
% Arg:
0
9
0
0
9
0
0
0
0
0
9
0
9
9
42
% R
% Ser:
0
9
0
9
9
59
17
50
9
0
0
0
9
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _